May 20, 2025, Tuesday
09:00-09:05
Ferenc Nagy: opening remarks
Chairman: Miklós Erdélyi
09:05-09:30
Nargis Karatayeva1,2, Lili Hegedűs1, Arindam Bhattacharjee3,4, Eszter Németh5, Ádám Póti5, Lőrinc Pongor6, Gábor Juhász3, Dávid Szüts5, Péter Burkovics1
1Laboratory of Replication and Genome Stability, Institute of Genetics, HUN-REN Biological Research Centre, Szeged
2Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged
3Lysosomal Degradation Research Group, Institute of Genetics, HUN-REN Biological Research Centre, Szeged
4Developmental Biology Group, Agharkar Research Institute, Pune, India
5Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest
6Cancer Genomics and Epigenetics Core Group, Hungarian Centre of Excellence for Molecular Medicine, Szeged
2Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged
3Lysosomal Degradation Research Group, Institute of Genetics, HUN-REN Biological Research Centre, Szeged
4Developmental Biology Group, Agharkar Research Institute, Pune, India
5Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest
6Cancer Genomics and Epigenetics Core Group, Hungarian Centre of Excellence for Molecular Medicine, Szeged
The effect of prolonged G-quadruplex stabilization on the functions of human cells
09:30-10:00
Petar Lambrev1, Parveen Akhtar1, Huang-Long Nguyen2, Howe-Siang Tan2
1Institute of Plant Biology, HUN-REN BRC, Szeged
2School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore
2School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore
Mapping the energy flow in photosynthetic supercomplexes
10:00-10:30
Csilla Fazakas1, Kinga Molnár1, Ádám Mészáros1, Tamás Dudás1, Attila E. Farkas1, István Krizbai1, Imola Wilhelm1
1Institute of Biophysics, HUN-REN Biological Research Centre, Szeged
MiR-146a-5p and TGF-β Collectively Regulate Brain Endothelial Paqr5 and Angiogenesis in Response to Tumour-derived Extracellular Vesicles
10:30-11:00
Break
CHAIRMAN: Szilvia Zita Tóth
11:00-11:30
Dominik Hirling1,2,*, Zsanett Zsófia Iván1,2,3,*, István Grexa1,2, Jonas Ammeling4, Tamás Micsik5, Katalin Dobra5, Farkas Sükösd6, Marc Aubreville7, Vivien Miczán1, Péter Horváth1,2,8,9
1Institute of Biochemistry, HUN-REN BRC, Szeged
2Single-cell Technologies Ltd., Szeged
3Doctoral School of Biology, University of Szeged, Szeged
4Technische Hochschule Ingolstadt, Ingolstadt, Germany
5Karolinska Institutet, Department of Oncology-Pathology, Solna, Sweden
6Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged
7Flensburg University of Applied Sciences, Flensburg, Germany
8Institute of AI for Health, Helmholtz Zentrum München, Neuherberg, Germany
9Institute for Molecular Medicine Finland, University of Helsinki, Helsinki
*These authors contributed equally to this work
2Single-cell Technologies Ltd., Szeged
3Doctoral School of Biology, University of Szeged, Szeged
4Technische Hochschule Ingolstadt, Ingolstadt, Germany
5Karolinska Institutet, Department of Oncology-Pathology, Solna, Sweden
6Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged
7Flensburg University of Applied Sciences, Flensburg, Germany
8Institute of AI for Health, Helmholtz Zentrum München, Neuherberg, Germany
9Institute for Molecular Medicine Finland, University of Helsinki, Helsinki
*These authors contributed equally to this work
Subtyping Mitosis: A Path Towards Human Level Performance
11:30-12:00
Zsófia Varga1,*, Eszter Anna Váradi1,2,*, Anna Zsófia Posher1,2,*, Gyöngyi Cinege1, Edina Erdős1, Bernadett Benyhe-Kis1,2, Anna Zsuzsanna Tihanyi1,2,4, Petros Tzerpos3, Krisztián P. Bene3, Anett Türk-Mázló5, Zsuzsa Muszka5, Nikolett Gémes6, Patrícia Neuperger6, Gábor J. Szebeni6, Márta Tóth7, Jolán E. Walter7, Ede Migh4, Péter Horváth4, Szilárd Póliska3, Bálint Csörgő4, László Nagy3,8,9,10, Zsolt Czimmerer1
1Laboratory of Macrophag Polarization, Institute of Genetics, HUN-REN Biological Research Centre, Szeged
2Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged
3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen
4Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged
5Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen
6Laboratory of Functional Genomics, Core Facility, HUN-REN Biological Research Centre, Szeged.
7Division of Allergy Immunology, Department of Pediatrics, University of South Florida at Johns Hopkins All Children’s Hospital, St. Petersburg, Florida, USA
8Department of Medicine, Johns Hopkins University School of Medicine, St. Petersburg, Florida, USA
9Department of Biological Chemistry, Johns Hopkins University School of Medicine, St. Petersburg, Florida, USA.
10Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA
*These authors contributed equally to this work.
2Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged
3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen
4Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged
5Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen
6Laboratory of Functional Genomics, Core Facility, HUN-REN Biological Research Centre, Szeged.
7Division of Allergy Immunology, Department of Pediatrics, University of South Florida at Johns Hopkins All Children’s Hospital, St. Petersburg, Florida, USA
8Department of Medicine, Johns Hopkins University School of Medicine, St. Petersburg, Florida, USA
9Department of Biological Chemistry, Johns Hopkins University School of Medicine, St. Petersburg, Florida, USA.
10Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA
*These authors contributed equally to this work.
Identification of synergistic interactions between the opposing macrophage polarization signals in macrophages
12:00-12:30
Rasik Shiekh Bin Hamid1,2, Fruzsina Nagy1,2, Nikolett Kaszler1, Ildikó Domonkos1, Magdolna Gombos1, Annamária Marton3, Csaba Vizler3, Eszter Molnár1, Aladár Pettkó-Szandtner3, László Bögre4, Attila Fehér1,5, Zoltán Magyar1
1Institute of Plant Biology, HUN-REN BRC, Szeged
2Doctoral School in Biology, Faculty of Science and Informatics, University of Szeged, Szeged
3Institute of Biochemistry, HUN-REN BRC, Szeged
4Department of Biological Sciences, Royal Holloway, University of London, Egham, Surrey, UK
5Department of Plant Biology, Faculty of Science and Informatics, University of Szeged, Szeged
2Doctoral School in Biology, Faculty of Science and Informatics, University of Szeged, Szeged
3Institute of Biochemistry, HUN-REN BRC, Szeged
4Department of Biological Sciences, Royal Holloway, University of London, Egham, Surrey, UK
5Department of Plant Biology, Faculty of Science and Informatics, University of Szeged, Szeged
RETINOBLASTOMA-RELATED has both canonical and noncanonical regulatory functions during thermo-morphogenic responses in Arabidopsis seedlings
12:30-14:00
LUNCH BREAK
CHAIRMAN: Mária Deli
14:00-14:30
Róbert Horváth1,2, Gergő Porkoláb1, Beatrix Magyaródi2, Imola Rajmon1,2, Kinga Kovács2, Nicolett Kanyó2, Sebestyén Varga1,2, Fruzsina Walter1, Ana Martins1, Beatrix Péter2, Inna Székács2, András Dér1, Mária Deli1
1Institute of Biophysics, HUN-REN Biological Research Centre, Szeged
2Nanobiosensorics Laboratory, MFA HUN-REN Centre for Energy Research, Budapest
2Nanobiosensorics Laboratory, MFA HUN-REN Centre for Energy Research, Budapest
Label-free biophysical tools for cellular adhesion, biomechanics, and single-cell injection
14:30-15:00
Bettina Magyari1, Anna Tácia Fülöp1, Dávid Kókai1,2, Franciska Tóth1, Gergő Mihály Balogh1,2, Sergio Andreu-Sánchez3, Gabriel Innocenti5, Jingyuan Fu3,4, Csaba Pál1, Alexandra Zhernakova3, Thomas Vogl5, Máté Manczinger1,2,6
1Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged
2HCEMM-BRC Systems Immunology Research Group, Szeged
3Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
4Department of Pediatrics, University of Groningen, University Medical Center Groningen,Groningen, the Netherlands
5Center for Cancer Research, Medical University of Vienna, Wien, Austria
6Department of Dermatology and Allergology, University of Szeged, Szeged
2HCEMM-BRC Systems Immunology Research Group, Szeged
3Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
4Department of Pediatrics, University of Groningen, University Medical Center Groningen,Groningen, the Netherlands
5Center for Cancer Research, Medical University of Vienna, Wien, Austria
6Department of Dermatology and Allergology, University of Szeged, Szeged
HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections
15:00-15:30
Melinda Horvát1, Zsanett Takács1, Erika Gábor1, Gábor Csordás2, Gábor J. Szebeni3, Tibor Kalmár4, Zoltán Maróti4, Peter Juma Ochieng4, Szabolcs Modok5, Viktor Honti1
1Drosophila Blood Cell Differentiation Group, Institute of Genetics, HUN-REN Biological Research Centre, Szeged
2Lysosomal Degradation Research Group, Institute of Genetics, HUN-REN Biological Research Centre, Szeged
3Laboratory of Functional Genomics, Core Facility, HUN-REN Biological Research Centre, Szeged
4Genetic Diagnostic Laboratory, Szent-Györgyi Albert Pediatric Clinic and Center for Child Health, Szeged
52nd Department of Internal Medicine and Cardiology Center, University of Szeged, Szeged
2Lysosomal Degradation Research Group, Institute of Genetics, HUN-REN Biological Research Centre, Szeged
3Laboratory of Functional Genomics, Core Facility, HUN-REN Biological Research Centre, Szeged
4Genetic Diagnostic Laboratory, Szent-Györgyi Albert Pediatric Clinic and Center for Child Health, Szeged
52nd Department of Internal Medicine and Cardiology Center, University of Szeged, Szeged
High-throughput drug repurposing screens in Drosophila leukemia models and human cell cultures
15:30-16:00
BREAK
CHAIRMAN: Péter Horváth
16:00-16:30
Roland Wirth1, Prateek Shetty1, Zoltán Bagi2, Kornél L. Kovács2, Gergely Maróti1
1Institute of Plant Biology, HUN-REN Biological Research Centre, Szeged
2Department of Biotechnology and Microbiology, University of Szeged, Szeged
2Department of Biotechnology and Microbiology, University of Szeged, Szeged
Multi-omics analysis of antibiotic-resistance genes in two industrial-scale anaerobic digesters
16:30-17:00
Judit P. Vigh1,2, Anna Kocsis1, Ana R. Santa-Maria1,3, Gergő Porkoláb1,5, Nóra Kucsápszky1, Emese Bélai4, Silvia Bolognin4, Jens C. Schwamborn4, Sándor Valkai1, András Kincses1, Anikó Szecskó1, Mária Mészáros1, Szilvia Veszelka1, Melinda Pirity1, András Dér1, Mária A. Deli1,*, Fruzsina R. Walter1,*
1Institute of Biophysics HUN-REN Biological Research Centre, Szeged
2University of Szeged, Szeged
3Wyss Institute, Harvard University, Boston, MA, USA
4University of Luxembourg, Belvaux, Luxembourg
5Trinity College Dublin, Dublin, Ireland
*These authors contributed equally to this work
2University of Szeged, Szeged
3Wyss Institute, Harvard University, Boston, MA, USA
4University of Luxembourg, Belvaux, Luxembourg
5Trinity College Dublin, Dublin, Ireland
*These authors contributed equally to this work
Engineering a Human Blood-Brain Barrier and Midbrain Organoid Brain-on-a-Chip Platform
17:00-17:30
Petra Szili1, Lejla Daruka1, Márton Simon Czikkely1,2,3, Zoltán Farkas1, Csaba Pál1
1Institute of Biochemistry, HUN-REN BRC, Szeged
2Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged
3Department of Forensic Medicine, Albert-Szent-Györgyi Medical School, University of Szeged, Szeged
2Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged
3Department of Forensic Medicine, Albert-Szent-Györgyi Medical School, University of Szeged, Szeged
Antibiotics of the future are prone to resistance in gram-negative pathogens
17:30-19:00
POSTER SESSION