Straub Napok 2022

2022. május 25. szerda

Elnök: Nagy Ferenc

(Szegedi Biológiai Kutatóközpont, Szeged)

10:00 – 10:05

Nagy Ferenc

(Szegedi Biológiai Kutatóközpont, Szeged)

Megnyitó

10:05 – 10:25

Sebők Katalin

Vállalati és Innovációs Elnökhelyettes
(NKFI Hivatal, Budapest)

A Nemzeti Laboratóriumok Program

10:25 – 10:45

Pál Csaba

(Biokémiai Intézet, SZBK Szeged;
Biotechnológiai Nemzeti Laboratórium, Szeged)

Antibiotikumok és ellenálló baktériumok

10:45 – 11:05

Kintses Bálint

(Biokémiai Intézet, SZBK Szeged;
Biotechnológiai Nemzeti Laboratórium, Szeged;
HCEMM-SZBK, Szeged)

ÚJGENERÁCIÓS BAKTERIOFÁG-TERAPEUTIKUMOK KUTATÁSA ÉS FEJLESZTÉSE

11:05 – 11:30

Kávészünet

11:30 – 11:50

Erdélyi Miklós

(Genetikai Intézet, SZBK, Szeged;
Biotechnológiai Nemzeti Laboratórium, Szeged)

"mRNS-LNP alapú eljárások meghonosítása és fejlesztése az SZBK-ban"

11:50 – 12:10

Mihály József

(Genetikai Intézet, SZBK, Szeged;
Biotechnológiai Nemzeti Laboratórium, Szeged)

Ritka betegségek modellezése és in vivo gyógyszer panel szűrési kísérletek ecetmuslicában

12:10 – 13:00

Biotechnológiai Nemzeti Laboratórium ünnepélyes átadása, sajtótájékoztató

13:00 – 14:00

Ebédszünet

Elnök: Siklós László

(Szegedi Biológiai Kutatóközpont, Főigazgatói Főosztály, Szeged)

14:00 – 14:50

Főigazgatói és gazdasági beszámoló

14:50 – 15:00

Kiváló dolgozói díjak átadása

15:00 – 15:10

Technikai szünet

15:10 – 15:30

A Straub plakett díjazottjának bemutatása, díjátadás és előadás

15:30 – 15:50

A Farkas Tibor plakett díjazottjának bemutatása, díjátadás és előadás

15:50 – 16:10

Kávészünet

16:10 – 16:30

A NEMZETI TUDÓSKÉPZŐ AKADÉMIA DÍJAZOTTJÁNAK ELŐADÁSA

Czikkely Márton1, Daruka Lejla1, Szili Petra1, Sipos Levente1, Elvin Maharramov1, Farkas Zoltán1, and Pál Csaba1

(1Biokémiai Intézet, Szintetikus és Rendszerbiológiai Egység, SZBK, Szeged)

Új antibiotikumok ellen kialakuló rezisztencia folyamatok rendszerszintű vizsgálata: rezisztenciamentes antibiotikum-baktérium párok azonosítása

16:30 – 16:50

A Qualitas Biologica Alapítvány pályázata 1. helyezettjének előadása

Jipa András1, Vedelek Viktor2, Merényi Zsolt3, Ürmösi Adél1, Takáts Szabolcs4, Kovács L Attila4, Horváth V Gábor1, Sinka Rita2, Juhász Gábor1,4

(1Genetikai Intézet, SZBK, Szeged;
2Genetikai Tanszék, Szegedi Tudományegyetem , Szeged;
3Biokémiai Intézet, SZBK, Szeged;
4ELTE Anatómiai, Sejt- és Fejlődésbiológiai Tanszék, Budapest)

Autofág gének kanonikus és nem-kanonikus szerepei

A Hotchkiss Alapítvány díjazottjainak előadásai:

16:50 – 17:00

Széles Eszter1,2, Nagy Krisztina3, Ábrahám Ágnes3,4 , Kovács Sándor1, Podmaniczki Anna1,2, Nagy Valéria1, Kovács László1, Galajda Péter3 és Tóth Szilvia Zita1

(1Növénybiológiai Intézet, SZBK, Szeged;
2Biológia Doktori Iskola, SZTE, Szeged;
3Biofizikai Intézet, SZBK, Szeged;
4Multidiszciplináris Orvostudományok Doktori Iskola, SZTE, Szeged):

Mikrofluidikai eszközök fejlesztése zöldalgák egysejt-szintű morfológiai és fotoszintetikus vizsgálataihoz

17:00 – 17:10

Kovács Szilárd1, Fodor Lili2, Domonkos Ágota2, Ferhan Ayaydin3,4, Laczi Krisztián1,5, Rákhely Gábor5,6 és Kaló Péter1,2

(1Növénybiológiai Intézet, SZBK, Szeged; 2Genetika és Biotechnológia Intézet, MATE, Gödöllő; 3Magyar Molekuláris Medicina Kiválósági Központ, Szeged; 4Mikroszkópos Sejtanalízis Laboratórium, SZBK, Szeged; 5Biotechnológiai Tanszék, SZTE, Szeged; 6Biofizikai Intézet, SZBK, Szeged)

Medicago truncatula NSP2 gén szerepe a gümőfejlődés szabályozásában

17:10 – 17:20

Patyi Gábor1,2, Hódi Barbara1,2, Solymosi Dániel1, Vass Imre1, Kós Péter1,3

(1Növénybiológiai Intézet, SZBK, Szeged; 2Biológiai Doktori Iskola, SZTE-TTIK, Szeged, 3Biotechnológiai Tanszék, SZTE-TTIK, Szeged):

Nehézfém bioriporterek érzékenységének fokozása transzporter hiányos Synechocystis PCC6803 cianobaktérium mutánsokban

17:20 – 19:00

Poszter szekció

19:00 -

fogadás, kutatói vacsora

2022. május 26. csütörtök

Chairman: László Zimányi

(Institute of Biophysics, BRC, Szeged)

9:00 – 9:25

Imola Wilhelm1, Kinga Molnár1, János Haskó1, Ádám Mészáros1, Attila E. Farkas1, Csilla Fazakas1 and István A. Krizbai1

(1Institute of Biophysics, BRC, Szeged)

Role of the neurovascular unit in brain metastasis formation

9:25 – 9:50

Andreas Mund1, Fabian Coscia1,2, Ede Migh3, Réka Hollandi3, Ferenc Kovács3,4, András Kriston3,4, Emma Lundberg5,6,7, Peter Horvath3,4,8,* and Matthias Mann1,9,*

(1Proteomics Program, NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;
2Spatial Proteomics Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany;
3Synthetic and Systems Biology Unit, BRC, Szeged;
4Single-Cell Technologies Ltd, Szeged;
5Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH - Royal Institute of Technology, Stockholm,Sweden;
6Department of Genetics, Stanford University, Stanford, USA;
7Chan Zuckerberg Biohub, San Francisco, USA;
8Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki,Finland;
9Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry,Martinsried, Germany
*These authors contributed equally to this work)

AI-driven Deep Visual Proteomics defines cell identity and heterogeneity

9:50 – 10:15

Péter Görög1,2, Szilárd Szikora1, Dávid Farkas1, Tamás Gajdos3, Miklós Erdélyi3, József Mihály1

(1Institute of Genetics, BRC, Szeged;
2Doctoral School of Multidisciplinary Medical Science, Faculty of Medicine, University of Szeged, Szeged;
3Department of Optics and Quantum Electronics, University of Szeged)

Flightless-I regulates sarcomere growth by promoting actin assembly

10:15 – 10:45

Break

10:45 – 11:10

Jinge Liu1, Ting Wang2, Xiaocheng Yu1, Attila Kereszt2, Hongyan Zhu1

(1Department of Plant & Soil Sciences, University of Kentucky, Lexington, USA;
2Institute of Plant Biology, BRC, Szeged)

Paired plant receptors restrict nodulation by Sinorhizobium symbionts carrying a strain-specific protein

11:10 – 11:35

Csaba Bödör1, Ákos Nagy1, Bence Bátai1, Lili Kotmayer1 Tamás László1 and Donát Alpár1

(1HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest)

Identification of novel molecular biomarkers in B-cell lymphomas

11:35 – 12:00

Jolán Csiszár1, Krisztina Bela1, Edit Horváth1, Ágnes Gallé1, Ádám Hajnal1, Bernát Tompa1, Riyazuddin, Riyazuddin1,2, Gábor Rigó2, László Szabados2 and Attila Fehér1,2

(1Department of Plant Biology, University of Szeged, Szeged;
2Institute of Plant Biology, BRC, Szeged)

New hub in the signal transduction network connecting redox regulation to plant development: the glutathione-linked antioxidant enzymes.

12:00 – 12:05

HR Pharma Kft - brief introduction and trade description /in Hungarian/

12:05 – 13:00

Lunch break

Chairman: Péter Horváth

(Institute of Biochemistry, BRC, Szeged)

13:00 – 13:25

Tamás Fekete1,2, Mária Mészáros1, Gaszton Vizsnyiczai1, Mária Deli1, Zsolt Szegletes1, László Zimányi1, Szilvia Veszelka1 and Lóránd Kelemen1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged)

Optically manipulated microtools to measure adhesion of the nanoparticle-targeting ligand glutathione to brain endothelial cells

13:25 – 13:50

Melinda E. Tóth1 , Brigitta Dukay1, Márta Sárközy2, Mária Péter1, Gábor Balogh1, Gergő Szűcs2, Ágnes Zvara3, Gábor J. Szebeni3, Petra Hajdu1, Zsófia Ruppert1, Csaba Csonka2, Bence Kővári6, Gábor Cserni6, Ferenc Kovács1,4,5, András Kriston1,4,5, Péter Horváth1,4,5, László G. Puskás3, Zsolt Török1, Tamás Csont2, László Vígh1 and Miklós Sántha1

(1Institute of Biochemistry, BRC, Szeged;
2MEDICS Research Group, Department of Biochemistry, University of Szeged Albert Szent-Györgyi Medical School, Szeged;
3Laboratory of Functional Genomics, BRC, Szeged;
4Single-Cell Technologies Ltd, Szeged;
5Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland;
6Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged)

Diverse effects of regular exercise in a mouse model of hyperlipidemia

13:50 – 14:15

Gyula Timinszky1, Massimo Lopes2, Ivan Ahel3

(1Lendület Laboratory of DNA Damage and Nuclear Dynamics, Institute of Genetics, BRC, Szeged;
2Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland;
3Sir William Dunn School of Pathology, University of Oxford, Oxford, UK)

TARG1 protects against toxic DNA ADP-ribosylation

14:15 – 14:45

Break

14:45 – 15:10

Gabriella Endre1, Sándor Jenei1, Hilda Tiricz1, Rui M. Lima1, Balaji Baburao Rathod1, Mohamad Anas Al Bouni1, Edit Tímár1, Gábor Tóth2, and Éva Kondorosi1

(1Institute of Plant Biology, BRC, Szeged;
2Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Szeged)

Can potent antimicrobial plant-derived NCR peptides and derivatives be the antibiotics of the future?

15:10 – 15:35

Karolina Pircs 1,2,3

(1 HCEMM-SU, Neurobiology and Neurodegenerative Diseases Research Group, Budapest, Hungary.
2 Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
3 Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, 221 84 Lund, Sweden)

Direct neural conversion: New possibilities to model late onset neurodegenerative diseases

15:35 – 16:00

Kaushik Nath Bhaumik1, Anasztázia Hetényi1, Gábor Olajos1, Ana Martins2, Réka Spohn2, Lukács Németh3, Balázs Jojart3, Petra Szili2,4, Anett Dunai2, Pramod K. Jangir2, Lejla Daruka2,5, Imre Földesi6, Diána Kata6, Csaba Pál2 and Tamás A. Martinek1

(1Department of Medical Chemistry, University of Szeged;
2Synthetic and Systems Biology Unit, BRC, Szeged;
3Institute of Food Engineering, University of Szeged, Szeged;
4Doctoral School of Multidisciplinary Medical Sciences, University of Szeged, Szeged;
5Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged;
6Department of Laboratory Medicine, University of Szeged, Szeged)

Rationally designed foldameric adjuvants enhance antibiotic efficacy via promoting membrane hyperpolarization

16:00 – 17:00

Poster section

2022. május 27. péntek

Chairman: Miklós Erdélyi

(Institute of Genetics, BRC, Szeged)

9:00 – 9:25

Tamás F. Polgár1,2, Valéria Meszlényi1,3, Bernát Nógrádi1,2,3, Krisztina Spisák1,2, Izabella Obál3,4, József I. Engelhardt3, László Siklós1 and Roland Patai1

(1Institute of Biophysics, BRC, Szeged;
2Theoretical Medicine Doctoral School, University of Szeged, Szeged;
3Department of Neurology, Albert Szent-Györgyi Health Centre, University of Szeged, Szeged;
4Department of Neurology, Aalborg University Hospital, Aalborg, Denmark)

Introducing an experimental motor neuron degeneration mouse model based on serum inoculation from amyotrophic lateral sclerosis patients

9:25 – 9:50

Zoltán Farkas1, Károly Kovács1,2, Zsuzsa Sarkadi1,2,3, Dorottya Kalapis1,2, Gergely Fekete1,2, Fanni Birtyik1, Ferhan Ayaydin4,5,6, Csaba Molnár1,7, Péter Horváth1,8,9, Csaba Pál1*, Balázs Papp1,2*

(1Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
2HCEMM-BRC Metabolic Systems Biology Lab, Szeged;
3Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged;
4Functional Cell Biology and Immunology Advanced Core Facility (FCBI), Hungarian Centre of Excellence for Molecular Medicine (HCEMM), Szeged;
5University of Szeged, Faculty of Medicine, Albert Szent-Györgyi Health Centre Interdisciplinary R&D and Innovation Center of Excellence, Szeged;
6Laboratory of Cellular Imaging, BRC, Szeged;
7Broad Institute of MIT and Harvard; Cambridge, MA, USA;
8Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki; Helsinki, Finland;
9Single-Cell Technologies Ltd., Szeged)

Gene loss and compensatory evolution promotes the emergence of morphological novelties

9:50 – 10:15

Gyöngyi Cinege1, Kirsten I Verster2, Zoltán Lipinszki3, Edit Ábrahám3, Rebecca Tarnopol2, Lilla B Magyar1, Zsuzsanna Darula4,5, Éva Kurucz1, Noah K Whiteman2 and István Andó1

(1Institute of Genetics, BRC, Szeged;
2Department of Integrative Biology, University of California, Berkeley, USA;
3Institute of Biochemistry, BRC, Szeged;
4Core Facilities, BRC, Szeged;
5Hungarian Centre of Excellence for Molecular Medicine (HCEMM), Szeged)

Horizontally transferred genes are required for an effective innate immune response

10:15 – 10:45

Break

10:45 – 11:10

Dávid Tóth1,2, Roland Tengölics3,4, André Vidal-Meireles1, László Kovács1, Soujanya Kuntam1, Alisdair R. Fernie5, Balázs Papp3,4 and Szilvia Z. Tóth1

(1Institute of Plant Biology, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3HCEMM-BRC Metabolic Systems Biology Lab, Szeged;
4Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
5Max-Planck-Institute of Molecular Plant Physiology, Potsdam-Golm, Germany)

Chloroplastic ascorbate content is a modulator of the plant metabolome

11:10 – 11:35

Balázs Enyedi1,2,3

(1HCEMM-SE Inflammatory Signaling Research Group;
2MTA-SE Lendület Tissue Damage Research Group of the Hungarian Academy of Sciences;
3Department of Physiology, Semmelweis University, Budapest)

Detecting extracellular gradients of inflammatory mediators with novel genetically encoded fluorescent biosensors

11:35 – 12:00

Orsolya Németh-Szatmári1, Ádám Györkei2, Dániel Varga3, Bálint Barna H. Kovács3, Nóra Igaz1, Kristóf Német1, Nikolett Bagi1, Bence Nagy-Mikó1, Dóra Balogh1, Zsolt Rázga4, Miklós Erdélyi3, Balázs Papp2, Mónika Kiricsi1, András Blastyák5, Martine A. Collart6, Imre M. Boros1 and Zoltán Villányi1

(1 Department of Biochemistry and Molecular Biology, University of Szeged, Szeged;
2 Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
3 Department of Optics and Quantum Electronics, University of Szeged, Szeged;
4Department of Pathology, Faculty of Medicine, University of Szeged, Szeged;
5 Institute of Genetics, BRC, Szeged;
6 Department of Microbiology and Molecular Medicine, Institute of Genetics and Genomics Geneva, Faculty of Medicine, University of Geneva, Switzerland)

Phase separated ribosome nascent chain complexes paused in translation are capable to continue expression of proteins playing role in genotoxic stress response upon DNA damage

12:00 – 12:05

Biocenter Kft – brief introduction and trade description /in Hungarian/

12:05 – 13:00

Lunch break

Chairman: Imre Vass

(Institute of Plant Biology, BRC, Szeged)

13:00 – 13:25

Sarshad Koderi Valappil1, Prateek Shetty2,3, Zoltán Deim1, Gabriella Terhes4, Edit Urbán4, Sándor Váczi5, Roland Patai6, Tamás Polgár6,7, Botond Zsombor Pertics8, György Schneider8, Tamás Kovács9,10 and Gábor Rákhely1,6

(1Department of Biotechnology, University of Szeged, Szeged;
2Institute of Plant Biology, BRC, Szeged;
3Doctorate School of Biology, University of Szeged, Szeged;
4Institute of Clinical Microbiology, University of Szeged, Szeged;
5Department of Pathophysiology, University of Szeged, Szeged;
6Institute of Biophysics, BRC, Szeged;
7Doctorate School of Theoretical Medicine, University of Szeged, Szeged;
8Department of Medical Microbiology and Immunology, University of Pécs, Pécs;
9Department of Biotechnology, Nanophagetherapy Center, Enviroinvest Corp., Pécs;
10Biopesticide Ltd., Pécs)

Phage infection reinstates antibiotic sensitivity in MDR Pseudomonas aeruginosa: A coevolutionary game between phage and its bacterial host

13:25 – 13:50

Gergő Mihály Balogh1,2, Leó Asztalos2, Csaba Pál2, Lajos Kemény2,3 and Máté Manczinger1,2

(1Institute of Biochemistry, BRC, Szeged;
2Albert Szent-Györgyi Medical School, University of Szeged, Szeged;
3HCEMM-USZ Skin Research Group, Szeged)

Revealing the invisible: effects of APOBEC3 mutagenesis on the adaptive immune recognition of SARS-CoV-2

13:50 – 14:15

Éva Bálint1 and Ildikó Unk1

(1Institute of Genetics, BRC, Szeged)

A new mechanism regulating enzyme activity: The role of metal cofactors in the transformation of DNA polymerase eta into an RNA synthesizing polymerase

14:15 – 14:45

Break

14:45 – 15:10

Dóra Faragó1, Laura Zsigmond1, Dániel Benyó1, Rubén Alcazar2, Gábor Rigó1, Ferhan Ayaydin3,4, Sahilu Ahmad Rabilu1, Aladár Pettkó-Szandtner5, László Szabados1

(1Institute of Plant Biology, BRC, Szeged;
2Facultat de Farmàcia, Universitat de Barcelona,Spain;
3Hungarian Centre of Excellence for Molecular Medicine (HCEMM) Nonprofit Ltd., Szeged;
4Cellular Imaging Laboratory, BRC, Szeged;
5Laboratory of Proteomics Research, BRC, Szeged)

Small paraquat resistance proteins confer drought tolerance to overexpressing Arabidopsis plants by interfering with paraquat and ABA responses

15:10 – 15:35

Roua Hassoun1,2, Melissa Herwig1,2, Melina Tangos1,2, Heidi Budde1,2, Saltanat Zhazykbayeva1,2, Marcel Sieme1,2, Simin Delalat1,2, Muhammad Jarkas1,2, and Nazha Hamdani1,2,3

1Institut für Forschung und Lehre (IFL), Department of Molecular and Experimental Cardiology, Ruhr University Bochum, Bochum, Germany;
2Department of Cardiology, St. Josef-Hospital and Bergmannsheil, Ruhr University Bochum, Bochum, Germany;
3HCEMM-Cardiovascular Research Group, Department of Pharmacology and Pharmacotherapy, University of Budapest, Budapest, Hungary)

Targeting oxidative stress and sarcomeric dysfunction in HFpEF

15:35 – 16:00

Liliána Tóth1, Renátó Kovács2, Györgyi Váradi3, Attila Borics4, Zoltán Kele3, Gábor K. Tóth3,5, Gábor Rákhely1,6, Gyula Batta7, Florentine Marx8 and László Galgóczy1,4

(1Department of Biotechnology, Faculty of Science and Informatics, University of Szeged, Szeged;
2Department of Medical Microbiology, Faculty of Medicine, University of Debrecen, Debrecen;
3Department of Medical Chemistry, Faculty of Medicine, University of Szeged, Szeged;
4Institute of Biochemistry, BRC, Szeged;
5MTA-SZTE Biomimetic Systems Research Group, University of Szeged, Szeged;
6Institute of Biophysics, BRC, Szeged;
7Department of Organic Chemistry, Faculty of Science and Technology, University of Debrecen, Debrecen;
8Institute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck)

New antifungal strategies - Characterization and application of Neosartorya (Aspergillus) fischeri antifungal protein 2 (NFAP2)

Posters

INSTITUTE OF BIOCHEMISTRY

Altering the substrate specificity of the CG-specific MpeI DNA-methytransferase by structure-guided mutagenesis

Pál Albert1,3, Bence Varga1,2,3, Györgyi Ferenc2 and Antal Kiss1

(1Institute of Biochemistry, BRC, Szeged;
2Institute of Plant Biology, Oligonucleotide Synthesis Laboratory, BRC, Szeged;
3Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged)

CometAnalyser: a user-friendly, open-source deep-learning microscopy tool for quantitative comet assay analysis.

Attila Baleon1, Sara Pignatta2, Chiara Arienti2, Antonella Carbonaro3, Peter Horvath1,4,5, Giovanni Martinelli2, Gastone Castellani6, Anna Tesei2 and Filippo Piccinini2

(1 Synthetic and Systems Biology Unit, BRC, Szeged;
2 IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy;
3 Department of Computer Science and Engineering (DISI), University of Bologna, Cesena, Italy;
4 Institute for Molecular Medicine Finland-FIMM, Helsinki Institute of Life Science-HiLIFE, University of Helsinki, Helsinki, Finland;
5 Single-Cell Technologies Ltd., Szeged;
6 Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy)

Large-scale Mutagenesis of Phage Tail Fibers to alter Host Specificity

Bálint Dénes Eszenyi1, Gábor Apjok1, Tóbiás Sári1, Bálint Kintses1

(1Synthetic and Systems Biology Unit, BRC, Szeged)

Investigating the sex-dependent effects of regular exercise training on muscle and brain tissue in a mouse model of hyperlipidemia

Brigitta Dukay1, Zsófia Bódai1, Alexandra Csefová1, Petra Hajdu1, Zsófia Ruppert1,2, Botond Penke3, Lívia Fülöp3, Kitti Szabó4, Anikó Keller-Pintér4, László Dux4, Imre Gombos1, Zsolt Török1, Miklós Sántha1 and Melinda E. Tóth1

(1Institute of Biochemistry, Biological Research Centre, Szeged;
2Doctoral School in Biology, University of Szeged, Szeged;
3Department of Medical Chemistry, and
4Muscle Adaptation Group, Department of Biochemistry, University of Szeged Albert Szent-Györgyi Medical School, Szeged)

Investigation of fever-like hyperthermia induced membrane-coupled events

Barbara Dukic1, Ádám Tiszlavicz1, Mária Péter1, Vanda Varga-Zsíros1, Gábor Balogh1, László Vígh1, Imre Gombos1, Zsolt Török1

(1Institute of Biochemistry, BRC, Szeged)

The effect of the heat shock on the intracellular membrane system of the fission yeast

Péter Gudmann1, Mária Péter1, Gábor Balogh1, Imre Gombos1, Zsolt Török1, Attila Glatz1

(1 Laboratory of Molecular Stress Biology, Institute of Biochemistry, BRC, Szeged)

Proteomic analysis of Botrytis cinerea induced noble rot development of Furmint grape berries

Éva Hunyadi-Gulyás1, Zsuzsanna Darula1,2, Miklós Pogány3

(1Laboratory of Proteomics Research, BRC, Szeged;
2Single Cell Omics Advanced Core Facility, HCEMM, Szeged;
3Plant Protection Institute, Centre for Agricultural Research, Budapest)

Quantitation using stable isotope laballed peptides to set up a diagnostic protein panel in the differentiation of renal carcinoma and normal kidney tissue

Éva Klement1,2, Áron Bartha3,4, Balázs Győrffy3,4, Zsuzsanna Darula1,2

(1 Single Cell Omics Advanced Core Facility, HCEMM, Szeged)

We bring metabolomics closer to your research

Tímea Körmöczi1,2, Dorottya Kalapis3,2, Dávid Tóth4,5, Valéria Nagy4, Szilvia Z. Tóth4, Balázs Papp3,2 and Roland Tengölics1,2

(1Metabolomics lab, BRC, Szeged;
2Hungarian Centre of Excellence for Molecular Medicine - Metabolic Systems Biology Lab, Szeged;
3Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
4Institute of Plant Biology, BRC, Szeged;
5Doctoral School of Biology, University of Szeged, Szeged)

10.

The role of correlated motions of conserved structural motifs in the activation mechanism of G protein-coupled receptors

Argha Mitra, Arijit Sarkar, Szabolcs Dvorácskó, Mária Harmati, Zsuzsánna Réthi-Nagy, Krisztina Buzás, Zoltán Lipinszki and Attila Borics

(Institute of Biochemistry, BRC, Szeged)

11.

Analysis of urinary O-glycopeptides: Systematic evaluation of a dataset using different search engines

Ádám Pap1, Katalin F. Medzihradszky1, Zsuzsanna Darula1,2

(1Laboratory of Proteomics Research, BRC, Szeged; 2Single Cell Omics Advanced Core Facility, HCEMM, Szeged)

12.

Investigating the effects of a small heat shock protein on metabolic syndrome in a transgenic mouse model

Zsófia Ruppert1, Bettina Rákóczi1, Brigitta Dukay1, Petra Hajdu1, Márta Sárközy2, Gergő Szűcs2, Tamás Csont2, Zsolt Török1, Miklós Sántha1, Melinda E. Tóth1

(1Institute of Biochemistry, BRC, Szeged;
2MEDICS Research Group, Department of Biochemistry, University of Szeged Albert Szent-Györgyi Medical School, Szeged)

13.

Genomic Epidemiology of Pathogenic Acinetobacter baumannii Hospital Outbreaks in Europe

Tamás Stirling1, Ildikó Lantos1, Eszter Ari1,2, Bálint Vásárhelyi1, Balázs Papp1, Bálint Kintses1

(1 Institute of Biochemistry, BRC, Szeged;
2 Department of Genetics, Eötvös Lóránd University, Budapest)

14.

The evolution of the yeast metabolome

Balázs Szappanos1,2,3, Roland Tengölics1,2, Gábor Grézal1,2, Dorottya Kalapis1,2, Dóra Spekhardt1,2, Stefánia Erdei1,2, Viktor Kilin1,2, Enrica Calvani5, Michael Mülleder4, Markus Ralser4 and Balázs Papp1,2

(1HCEMM-BRC Metabolic Systems Biology Research Group, Szeged;
2Institute of Biochemistry, Synthetic and Systems Biology Unit, BRC, Szeged;
3Department of Biotechnology, University of Szeged, Szeged;
4Department of Biochemistry, Charité University Medicine, Berlin, Germany;
5Department of Biochemistry, University of Cambridge, The Francis Crick Institute, London, NW1 1AT, UK)

15.

Rational design of balanced dual-targeting antibiotics with limited resistance

Petra Szili1, Tihomir Tomašič2, Martina Durcik2, Ákos Nyerges1, Csaba Pál2

(1Institute of Biochemistry, BRC, Szeged;
2 University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia)

16.

Investigation of tumor heterogeneity: a novel, laser microdissection-coupled lipidomic method

Vanda Varga-Zsíros1, Mária Péter1, Ede Migh1, Annamária Marton1, Aladár Pettkó-Szandtner2, Imre Gombos1, Barbara Dukic1, Zsuzsanna Darula2,3, Csaba Vizler1, László Tiszlavicz4, Péter Horváth1, László Vígh1, Zsolt Török1, Gábor Balogh1

(1 Institute of Biochemistry, BRC, Szeged;
2 Laboratory of Proteomics Research, BRC, Szeged;
3 Single Cell Omics Advanced Core Facility, HCEMM, Szeged;
4 Department of Pathology, Faculty of Medicine, University of Szeged, Szeged)

INSTITUTE OF BIOPHYSICS

17.

Single-cell level quorum sensing response of Pseudomonas aeruginosa under dynamic environmental conditions

Ágnes Ábrahám1,2, Krisztina Nagy1, Eszter Csákvári1, László Dér1, Imre Pap1,2, Rebeka Lukács1, Vanda Varga-Zsíros1,3 and Péter Galajda1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged;
3Institute of Biochemistry, BRC, Szeged)

18.

IL-6 and IL-10 induced morphological changes in brain microvessels isolated from wild type and ApoB-100 transgenic mice

Beáta Barabási1, Lilla Barna1, András Harazin1, Melinda Tóth2, Brigitta Dukay2, Miklós Sántha2, Zsófia Hoyk1 and Mária A. Deli1

(1Institute of Biophysics, BRC, Szeged;
2Institute of Biochemistry, BRC, Szeged)

19.

The effect of adenosine on the integrity of the blood-brain barrier

Lilla Barna1,2, András Harazin1, Gabriela Hurtado-Alvarado3, Krisztián Laczi4, Gábor Rákhely1,4, Beatriz Gomez-Gonzalez3 and Mária A. Deli1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School in Biology, University of Szeged, Szeged;
3Department of Reproductive Biology, Metropolitan Autonomous University, Mexico City, Mexico;
4Department of Biotechnology, University of Szeged, Szeged)

20.

Investigation of the galectin-1 protein on culture models of biological barriers

Alexandra Bocsik1, Ilona Gróf1, Enikő Szabó2, Norbert Imre3, Theodora M. Niczky1, Anna Hegyi1, Ágnes Czibula4, Éva Monostori4, Tamás Martinek3 and Mária A. Deli1

(1Institute of Biophysics, BRC, Szeged;
2 Laboratory of Functional Genomics, BRC, Szeged;
3Department of Medical Chemistry, University of Szeged, Szeged;
4 Institute of Genetics, BRC, Szeged)

21.

Microbial tolerance to petroleum products in inverse emulsions

Attila Bodor1,2, Máté Nagy2, Katalin Perei2 and Gábor Rákhely1,2

(1Institute of Biophysics, BRC, Szeged;
2Department of Biotechnology, University of Szeged, Szeged)

22.

A novel approach in heart-rate-variability analysis based on modified Poincaré plots

András Búzás1, Tamás Horváth2 and András Dér1

(1Institute of Biophysics, BRC, Szeged;
2Centre of Cardiology, Medical Faculty of the University of Szeged, Szeged)

23.

Boundary scattering and the spatial distribution of confined active particles

András Búzás1, Roberto Di Leonardo2, Pál Ormos1 and Gaszton Vizsnyiczai1

(1Institute of Biophysics, BRC, Szeged;
2Dipartimento di Fisica, Università di Roma “Sapienza”, Roma, Italy)

24.

Inflammation induced alterations in nanomechanical characteristics of brain seeking tumor cells

Katalin Csonti3,4, Anna Poscher2, Csilla Fazakas1, Kinga Molnár1, Imola Wilhelm1, István Krizbai1, Márta Dorogi4 and Attila Gergely Végh1

(1Institute of Biophysics, BRC, Szeged;
2Faculty of Science and Informatics, University of Szeged, Szeged;
3Doctoral School of Physics, University of Szeged, Szeged;
4Semilab Semiconductor Physics Laboratory Co. Ltd., Budapest)

25.

Measuring the binding force between glutathione-functionalized microtools and blood-brain barrier cells with optical tweezers

Tamás Fekete1,2, Mária Mészáros1, Gaszton Vizsnyiczai1, Mária Deli1, Zsolt Szegletes1, László Zimányi1, Szilvia Veszelka1 and Lóránd Kelemen1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged)

26.

DIET, a radically new biogas technology heaves in sight

Noémi Gönczi1,3, Roland Wirth2, Márk Szuhaj1,3, Gábor Rákhely1,3, Kornél L. Kovács1,4 and Zoltán Bagi1,3

(1Department of Biotechnology, University of Szeged, Szeged;
2Institute of Plant Biology, BRC, Szeged;
3Institute of Biophysics, BRC, Szeged;
4Department of Oral Biology and Experimental Dental Research, University of Szeged, Szeged)

27.

Examination of the intracellular targeting and shuttle actions of the WYKYW pentapeptide for biomolecule cargoes

Ilona Gróf1, Alexandra Bocsik1, Enikő Szabó2, Imre Norbert3, Anna Hegyi1, Ágnes Czibula4, Éva Monostori4, Tamás Martinek3 and Mária A. Deli1

(1Institute of Biophysics, BRC, Szeged;
2Laboratory of Functional Genomics, BRC, Szeged;
3Department of Medical Chemistry, University of Szeged, Szeged;
4Institute of Genetics, BRC, Szeged)

28.

Micromanipulation of bacterial cells by optical tweezers and microfluidics

Kiss Rebeka1,2, Ágnes Ábrahám1,3, Krisztina Nagy1, Gaszton Vizsnyiczai1, László Dér1, Lóránd Kelemen1 and Péter Galajda1

(1Institute of Biophysics, BRC, Szeged;
2 Institute of Physics, University of Szeged, Szeged;
3Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged)

29.

Cellulose degradation by anaerobic fungi

Etelka Kovács1, Zoltán Bagi1,2, Gábor Rákhely1,2 and Kornél L. Kovács1,3

(1Department of Biotechnology, University of Szeged, Szeged;
2Institute of Biophysics, BRC, Szeged;
3Department of Oral Biology and Experimental Dental Research, University of Szeged, Szeged

30.

Cerebral pericytes and endothelial cells communicate through inflammasome dependent signals

Ádám Mészáros1, Mihály Kozma1,2, Ádám Nyúl-Tóth1, Kinga Molnár1,2, Zsófia Hernádi1, Csilla Fazakas1, Attila E Farkas1, Imola Wilhelm1 and István Krizbai1

(1Institute of Biophysics, BRC, Szeged;
2Theoretical Medicine Doctoral School, University of Szeged, Szeged)

31.

Quinone-binding site of type VI sulfide:quinone oxidoreductases

Nikolett Miklovics1, Ágnes Duzs1, Gábor Paragi2,3, Fanni Balogh1, Gábor Rákhely1,4 and András Tóth1,4

(1Institute of Biophysics, BRC, Szeged;
2Institute of Physics, University of Pécs, Pécs;
3MTA-SZTE Biomimetic Systems Research Group, Department of Medical Chemistry, University of Szeged, Szeged;
4Department of Biotechnology, University of Szeged, Szeged)

32.

Impact of Tryptophan-Retinal Interaction on the Retinal Excited State and Photocycle of Gloebacter Rhodopsin

Ramprasad Misra1, Ishita Das1, András Dér2, Gábor Steinbach2,3, Kwang-Hwan Jung4, László Zimányi2 and Mordechai Sheves1

(1Department of Molecular Chemistry and Materials Science, Weizmann Institute of Science, Rehovot, Israel;
2Institute of Biophysics, BRC, Szeged;
3Cellular Imaging Laboratory, BRC, Szeged;
4Department of Life Science and Institute of Biological Interfaces, Sogang University, Seoul, South Korea)

33.

Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury

Kinga Molnár1,2, Bernát Nógrádi1,3, Rebeka Kristóf1,2,4, Ádám Mészáros1, Krisztián Pajer4, László Siklós1, Antal Nógrádi4, Imola Wilhelm1 and István Krizbai1

34.

Emergence of phage resistant Eschericia coli mutants in microstructured environment

Krisztina Nagy1, Sarshad Koderi Valappil2, Trung Phan3, László Dér1, Gábor Rákhely1,2, Péter Galajda1 and Robert H. Austin3

(1Institute of Biophysics, BRC, Szeged;
2Department of Biotechnology, University of Szeged, Szeged;
3Department of Physics, Princeton University, Princeton, NJ, USA)

35.

A novel simulation approach addressing larger biological systems: Particle Swarm Optimization

Zoltán Násztor1, János Horváth1 and András Dér1

(1Institute of Biophysics, BRC, Szeged)

36.

Computational investigation of the graphene oxide interaction with human serum albumin

Zoltán Násztor1, János Horváth1, András Dér1 and Ferenc Bogár2

(1Institute of Biophysics, BRC, Szeged; 2MTA-SZTE Biomimetic Systems Research Group, University of Szeged, Szeged)

37.

Effect of solvation environment on the distributed kinetics of NADH cofactor: a simulation study

Zoltán Násztor1, János Horváth1 and András Dér1

(1Institute of Biophysics, BRC, Szeged)

38.

Development and applications of bacterial “mother machines”

Imre Pap1,2, Krisztina Nagy1, Ágnes Ábrahám1,2 and Péter Galajda1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Multidisciplinary Medical Science, University of Szeged, Szeged)

39.

Integrated optical Mach-Zehnder interferometer biosensor to detect the penetration of SARS-CoV-2 Spike Protein across a human Blood-Brain Barrier cell-culture model system

Dániel Petrovszki1, Fruzsina R. Walter1, Judit P. Vigh1,3, Anna Kocsis1, Sándor Valkai1, Mária A. Deli1 and András Dér1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Multidisciplinary Medical Sciences, University of Szeged, Szeged;
3Doctoral School of Biology, University of Szeged, Szeged)

40.

Photobleaching alters quantified morphological features of microglia and the number of neuronal profiles during immunofluorescent imaging

Tamás F. Polgár1,2, Krisztina Spisák1,2, László Siklós1 and Roland Patai1

(1Institute of Biophysics, BRC, Szeged;
2Theoretical Medicine Doctoral School, University of Szeged, Szeged)

41.

Metastasis related adhesion pattern of brain seeking tumor cells in contact with brain endothelium

Anna Poscher2, Katalin Csonti3,4 Csilla Fazakas1, Kinga Molnár1, Imola Wilhelm1, István Krizbai1, and Attila Gergely Végh1

42.

Triple ligand-targeted nanoparticles cross the blood-brain barrier in vitro and enter human midbrain organoids

Gergő Porkoláb1,2, Mária Mészáros1, Anikó Szecskó1, Nóra Kondor1, Györgyi Ferenc3, Zoltán Kóta1, Tibor Páli1, Judit P. Vigh1,2, Fruzsina R. Walter1, Silvia Bolognin4, Jens C. Schwamborn4, Jeng-Shiung Jan5, Mária A. Deli1 and Szilvia Veszelka1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Institute of Plant Biology, BRC, Szeged;
4Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg;
5Department of Chemical Engineering, National Cheng Kung University, Tainan, Taiwan)

43.

Passive transfer of blood sera from ALS patients with known genetic alterations results in elevated calcium levels and motor neuronal loss in mice

Krisztina Spisák1,2, Tamás F. Polgár1,2, Valéria Meszlényi1,3, Bernát Nógrádi1,2,3, Izabella Obál3,4, József I. Engelhardt3, László Siklós1 and Roland Patai1

44.

Examination of viral peptide-targeted nanoparticles on a culture model of the blood-brain barrier

Anikó Szecskó1, Mária Mészáros1, Gergő Porkoláb1,2, Vera Neves3, Marco Cavaco3, Miguel A.R.B. Castanho3, Mária A. Deli1 and Szilvia Veszelka1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal)

45.

In vitro confrontation assay of Aspergillus clavatus and Trichoderma reesei

Csilla Szűcs1, Etelka Kovács1, Zoltán Bagi1, Gábor Rákhely1,2 and Kornél L. Kovács1,3

(1Department of Biotechnology, University of Szeged, Szeged;
2Institute of Biophysics, BRC, Szeged;
ű 3Department of Oral Biology and Experimental Dental Research, University of Szeged, Szeged)

46.

Co-culture of human brain organoids with blood-brain barrier model on a microfluidic biochip platform: morphological and functional characterization

Judit P. Vigh1,2, Fruzsina R. Walter1, Anna Kocsis1, Gergő Porkoláb1,2, Ilona Gróf1, Lilla Barna1, András Kincses1, Sándor Valkai1, Silvia Bolognin3, Jens C. Schwamborn3, András Dér1 and Mária A. Deli1

(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg)

INSTITUTE OF GENETICS

47.

Role of lysosomal Trpml/mucolipin-1 calcium channel in autophagic flux

Hussein Abuammar1,3, Arindam Bhattacharjee1, Gabor Juhasz1,2

(1Institute of Genetics, BRC, Szeged;
2Department of Anatomy, Cell and Development Biology, Eötvös Loránd University, Budapest;
3University of Szeged, Szeged)

48.

New role of ncPRC1 core member YAF2 in neural development

Lili Adorján1,2, Enikő Sutus1,3, Melinda Katalin Pirity1

(1Institute of Genetics, BRC, Szeged;
2Faculty of Science and Informatics, University of Szeged, Szeged;
3Doctoral School in Biology, Faculty of Science and Informatics, University of Szeged, Szeged)

49.

Drosophila PIWI protein utilizes molecular mimicry of SUMO to recruit Su(var)2-10 to the site of transposon repression

Melinda Bence1, Ákos Gyetvai1, Ferenc Jankovics1, Beáta G. Vértessy 2,3, Miklós Erdélyi1

(1Institute of Genetics, BRC, Szeged;
2Department of Applied Biotechnology and Food Sciences, Budapest University of Technology and Economics, Budapest;
3Institute of Enzymology, Research Centre for Natural Sciences, Budapest)

50.

Parallel mechanisms ensure the robust nuclear import of actin

Péter Borkúti, Ildikó Maruzs-Kristó, Anikó Szabó, Zoltán Kovács and Péter Vilmos

(Institute of Genetics, BRC, Szeged)

51.

Investigating the role of Drosophila Snx25 in the endomembrane system of nephrocytes

Dalma Feil-Börcsök1, Tamás Maruzs1, Enikő Lakatos1, Gábor Juhász1, Péter Lőrincz2, András Blastyák1 and Gábor Juhász1,2

(1Institute of Genetics, BRC, Szeged;
2Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest)

52.

High-throughput screening for small molecule modulators of the PCNA ubiquitination cascade

Gabriel Fenteany1,2,8,*, Gaurav Sharma3,4,8, Paras Gaur 3,5, Attila Borics6, Edit Wéber1, Ernő Kiss 2, and Lajos Haracska 3,7, 9,*

(1Department of Medical Chemistry, University of Szeged, Szeged;
2 Institute of Genetics, BRC, Szeged;
3HCEMM-BRC Mutagenesis and Carcinogenesis Research Group, Institute of Genetics, BRC, Szeged;
4Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged;
5Carver College of Medicine, University of Iowa, Iowa City, USA;
6Laboratory of Chemical Biology, Institute of Biochemistry, BRC, Szeged;
7Delta Bio 2000 Ltd., Szeged;
8These authors contributed equally
9Lead contact)

53.

There and back again: the heterogeneity of Drosophila hemocytes

Erika Gábor1, Aliz Géczi1,2, Bayan Kharrat1,2, Ede Migh3, Attila Beleon3, Péter Horváth3, Bence Széplaki4, Márton Enyedi4, Lajos Pintér4, Lajos Haracska4, Balázs Vedelek5 and Viktor Honti1

(1Drosophila Blood Cell Differentiation Group, Institute of Genetics, BRC, Szeged;
2 Department of Biology, Faculty of Science and Informatics, University of Szeged, Szeged;
3Laboratory of Microscopic Image Analysis and Machine Learning, Institute of Biochemistry, BRC, Szeged;
4Laboratory of Mutagenesis and Carcinogenesis Research, Institute of Genetics, BRC, Szeged;
5Laboratory of Actin Cytoskeleton Regulation, Institute of Genetics, BRC, Szeged)

54.

LINE1 retrotransposition, a major character in human carcinogenesis? - a study based on human tumor bank data

Khaldoon Sadiq Ahmed Abdullah1,2, Réka Karkas 1,2, Gabriella Pankotai-Bodó3, Sükösd Farkas3, Mátés Lajos1

(1Institute of Genetics, BRC, Szeged;
2Doctoral School of Multidisciplinary Medical Sciences, Faculty of Medicine, University of Szeged,Szeged;
3Department of Pathology, Faculty of Medicine, University of Szeged, Szeged)

55.

A new role for Myeloid leukemia factor (Mlf) in controlling lamellocyte fate in Drosophila melanogaster

Bayan Kharrat1,3, Nikolett Virág1,2 and Viktor Honti1

56.

Cell fate defining role of RYBP in early stage of cardiac differentiation

Lilla Kókity1,2, Surya Henry1, Melinda Katalin Pirity1

(1Institute of Genetics, BRC, Szeged;
2Doctoral School in Biology, Faculty of Science and Informatics, University of Szeged, Szeged)

57.

Nuclear import dynamics of the Drosophila Moesin protein

Zoltán Kovács, Ildikó Kristó, Péter Borkúti and Péter Vilmos

(Institute of Genetics, BRC, Szeged)

58.

Assessing the performance of ten pathogenicity prediction algorithms on a dataset of missense BRCA1 and BRCA2 mutations

Erda Qorri1, Bertalan Takács1, Alexandra Gráf1, Márton Zs. Enyedi2, Lajos Pintér2, Ernő Kiss1, Lajos Haracska1,2

(1HCEMM-BRC Mutagenesis and Carcinogenesis Research Group, Institute of Genetics, BRC, Szeged;
2Delta Bio 2000 Ltd., Szeged)

59.

Studying Drosophila blood cell plasticity using primary blood cell cultures

Enikő Sutus1, Erika Gábor1, Bayan Kharrat1, Ferenc Jankovics2, Rita Sinka3 and Viktor Honti1

(1Drosophila Blood Cell Differentiation Group, Institute of Genetics, BRC, Szeged;
2Laboratory of Drosophila Germ Cell Differentiation, Institute of Genetics, BRC, Szeged;
3Department of Genetics, Faculty of Science and Informatics, University of Szeged, Szeged)

INSTITUTE OF PLANT BIOLOGY

60.

Two-dimensional electronic spectroscopy of a minimal Photosystem I complex reveals the rate of primary charge separation

Parveen Akhtar1,2,3, Ido Caspy4, Nathan Nelson4, Howe-Siang Tan2 and Petar H. Lambrev1

(1Institute of Plant Biology, BRC, Szeged;
2 School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore;
3 ELI-ALPS, ELI-HU Nonprofit Ltd., BRC, Szeged;
4 The George S. Wise Faculty of Life Sciences, Tel Aviv University, Israel)

61.

Metagenomic investigation of the bacterial consortium of a thermal water reservoir

Csenge Bakó1,2, Krisztián Laczi1,2 and Péter B. Kós1,2

(1Department of Biotechnology, Faculty of Science and Informatics, University of Szeged, Szeged;
2Institute of Plant Biology, BRC, Szeged)

62.

The investigation of nitrogen fixation in Amorpha fruticosa

Benedikta Balla1,2, Rui Lima1 and Attila Kereszt1

(1Institute of Plant Biology, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged)

63.

Aromatic hydrocarbon tolerating, halotolerant bacteria from a thermal water reservoir

Boglárka Bereczky1,2, Gábor Patyi1, Lilla Futó-Dékány1, Krisztián Laczi1,2 and Péter B. Kós1,2

(1Institute of Plant Biology, BRC, Szeged;
2Department of Biotechnology, Faculty of Science and Informatics, University of Szeged, Szeged)

64.

Energy transfer from Phycobilisomes to Photosystem I in a model system

Avratanu Biswas1,2, Zita Szegletes1,3, Petar H. Lambrev1 and Parveen Akhtar1

(1Institute of Plant Biology, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Institute of Chemistry, Faculty of Sciences and Informatics, University of Szeged, Szeged)

65.

The AtCRK5 protein kinase is required to maintain the ROS NO balance affecting the PIN2-mediated root gravitropic response in Arabidopsis

Ágnes Cséplő1, Laura Zsigmond1, Norbert Andrási1, Imran Abou1,2, Nitin Labhane3, Andrea Pető 4,5, Zsuzsanna Kolbert4, Hajnalka Kovács1, Gábor Steinbach1,6, László Szabados1, Attila Fehér1,4 and Gábor Rigó1

(1Institute of Plant Biology, BRC, Szeged;
2Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden;
3Department of Botany, Bhavan’s College Andheri West, Mumbai, India;
4Department of Plant Biology, University of Szeged, Szeged;
5Food Chain Safety Center Nonprofit Ltd., Budapest;
6Cellular Imaging Laboratory, BRC, Szeged)

66.

Synthesis and characterization of the secondary structure of oligonucleotides containing 2'-deoxy-5-hydroxyuridine

Györgyi Ferenc1, Zoltán Kupihár2, Zoltán Váradi2, Éva Klement3, Attila Borics3, Zoltán Lipinszki3, Zsuzsanna Réthi-Nagy3, Gábor Paragi4,5 and Lajos Kovács2

(1Institute of Plant Biology, BRC, Szeged;
2Department of Medicinal Chemistry, University of Szeged, Szeged;
3Institute of Biochemistry, BRC, Szeged;
4Biomimetic Systems Research Group, MTA-SZTE, Szeged;
5Institute of Physics, University of Pécs, Pécs)

67.

Role of Arabidopsis E2F transcription factors in root and shoot developmental processes

Katalin Gémes1,2, Nikolett Kaszler1,2, Márta Szabó2, Péter Benkő1, Zoltán Magyar1 and Attila Fehér1,2

(1Institute of Plant Biology, BRC, Szeged;
2Department of Plant Biology, University of Szeged, Szeged)

68.

E2Fs regulate a cell size controller through modulating the expression of MYB3R4

Magdolna Gombos1, Dóri Bernula1, Masaki Ito2, Moussa Benhamed3, Cécile Raynaud3, László Bögre4 and Zoltán Magyar1

(1Institute of Plant Biology, BRC, Szeged;
2School of Biological Science and Technology, College of Science and Engineering, Kanazawa University, Kanazawa, Japan;
3Institute of Plant Sciences Paris Saclay, France;
4Royal Holloway University of London, Egham, UK)

69.

Predicted phosphorilation and dimerization of certain LBD transcription factors expressed in Brachypodium distachyon based on molecular dynamics

Attila Hlacs1,3, Magdolna Gombos1, Attila Borics2 and János Györgyey1

(1Institute of Plant Biology, BRC, Szeged;
2Institute of Biochemistry, BRC, Szeged;
3Doctoral School of Biology, University of Szeged, Szeged)

70.

The Development of Imaging Setup for Whole Cell-Based Biosensor

Shyam Jee1,2, Kamal Kant2, Ildikó Valkony2, Ranti Dev Shukla3, Tamás Fehér3, Evrim Elcin4, Hüseyin Avni Öktem4 and Ferhan Ayaydin1,2

(1Hungarian Centre of Excellence for Molecular Medicine (HCEMM) Nonprofit Ltd., Szeged;
2Cellular Imaging Laboratory, BRC, Szeged;
3Institute of Biochemistry, BRC, Szeged;
4Department of Biotechnology, Middle East Technical University, Ankara, Turkey)

71.

The role of Arabidopsis thaliana mitochondrial proteins in stress responses

Annabella Juhász-Erdélyi1, Ildikó Valkai1, Gábor Rigó1, Ágnes Szepesi2, Dávid Alexa1, Niklas Körber 3, Fabio Fiorani3, László Szabados1 and Laura Zsigmond1

(1Institute of Plant Biology, BRC, Szeged;
2Department of Plant Biology, University of Szeged, Szeged;
3Forschungszentrum Jülich, Jülich, Germany)

72.

Salt-stress induced changes in the supramolecular organization of the photosynthetic membranes of Chlamydomonas reinhardtii and Euglena gracilis

Sai Divya Kanna1, 2, Parveen Akhtar1, Satyabala Neelam3, Elsin Raju3, Srilatha Nama3, Petar H. Lambrev1, Tímea Ottília Kóbori4, Ágnes Dergez4, Ildikó Domonkos1, Győző Garab1, Rajagopal Subramanyam3 and Bettina Ughy1

(1Institute of Plant Biology, BRC, Szeged;
2Biological Doctoral School, University of Szeged, Szeged;
3Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, India;
4Division for Biotechnology, Bay Zoltán Nonprofit Ltd. for Applied Research, Szeged)

73.

Analysis of abiotic stress tolerance in selected genes of Arabidopsis thaliana

Kamal Kant, Gábor Rigó, Norbert Andrási, László Szabados and Laura Zsigmond

(Institute of Plant Biology, BRC, Szeged)

74.

NMD mediated RNA quality control in Chlamydomonas reinhardtii

Soujanya Kuntam1, André Vidal-Meireles1, Csaba Péter1,2, Szilvia Z. Tóth1 and Dániel Silhavy1

(1Institute of Plant Biology, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged)

75.

Characterization of activities of lignin synthetic genes for monitoring triploid heterosis in willow (Salix sp.) shoots in relation to biogas fermentation productivity from woody tissues

Nikolett László1,3, Zoltán Zombori1, András Cseri1, László Sass1, Györgyi Ferenc1, Zoltán Bagi2, Kornél L. Kovács2 and Dénes Dudits1

(1Institute of Plant Biology, BRC, Szeged;
2Department of Biotechnology, University of Szeged, Szeged;
3Department of Plant Biology, University of Szeged, Szeged)

76.

Functional analysis of phytochrome B phosphorylation in Arabidopsis thaliana

Valentina Madár1,2, Éva Ádám1, Ferenc Nagy1 and András Viczián1

(1Institute of Plant Biology, BRC, Szeged;
2Department of Plant Biology, Faculty of Sciences and Informatics, University of Szeged, Szeged)

77.

Dependence of the rate-limiting steps in the dark-to-light transition of Photosystem II on the lipidic environment of the reaction center

Melinda Magyar1, Parveen Akhtar1, Gábor Sipka1, Wenhui Han2, Xingyue Li2, Guangye Han2, Jian-Ren Shen2,3, Petar H. Lambrev1 and Győző Garab1,4

(1Institute of Plant Biology, BRC, Szeged;
2Photosynthesis Research Center, Key Laboratory of Photobiology, Institute of Botany, Chinese Academy of Sciences, Beijing, China;
3Research Institute for Interdisciplinary Science and Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan;
4Faculty of Science, University of Ostrava, Ostrava, Czech Republic)

78.

The lack of E2FA but not E2FB fully restores the rbr1-2 mutant phenotype

Eszter Molnár1, Rasik Shiekh1,2, Fruzsina Nagy1 and Zoltán Magyar1.

(1Institute of Plant Biology, BRC, Szeged;
2Biological Doctoral School, University of Szeged, Szeged)

79.

The Brassica E2FB under the control of its own rapeseed promoter could replace Arabidopsis E2FB

Fruzsina Nagy1, Tünde Vaskó-Leviczky1, Aladár Pettkó-Szandtner2 and Zoltán Magyar1

(1Institute of Plant Biology, BRC, Szeged;
2Institute of Biochemistry, BRC, Szeged)

80.

Bacterial growth phases in Synechococcus elongatus PCC7942

Sarolta Nagyapati1,2, Kinga Böde1,2, Sai Divya Kanna1, Aladár Pettko-Szandtner3, László Szilak4 and Bettina Ughy1

(1Institute of Plant Biology, BRC, Szeged;
2Biological Doctoral School, University of Szeged, Szeged;
3Laboratory of Proteomics Research, BRC, Szeged;
4Szilak Laboratory Ltd., Szeged)

81.

Characterization of the wave phenomenon in flash-induced fluorescence relaxation and its application to study cyclic electron pathways in microalgae

Priyanka Patil, Milán Szabó and Imre Vass

(Institute of Plant Biology, BRC, Szeged)

82.

The role of minor phytochromes in red light regulated photomorphogenesis

Csaba Péter1, Éva Ádám1, Gábor Grézal2, Anita Hajdu1, László Kozma-Bognár1,3, Dániel Silhavy1, András Viczián1 and Ferenc Nagy1

(1Institute of Plant Biology, BRC, Szeged;
2Institute of Biochemistry, BRC, Szeged;
3Department of Genetics, Faculty of Sciences and Informatics, University of Szeged, Szeged)

83.

Electric current production by Parachlorella kessleri strains is correlated to their photosynthetic performance

Nia Petrova, Tünde Tóth, Gergely Maróti and Szilvia Z. Tóth

(Institute of Plant Biology, BRC, Szeged)

84.

The Arabidopsis Retinoblastoma-related (RBR) and its interactions: a proteomic view of a major plant growth regulator.

Aladár Pettkó-Szandtner1, Éva Hunyady-Gulyás1, László Bögre2 and Zoltán Magyar3

(1Laboratory of Proteomics Research, BRC, Szeged, Hungary;
2Royal Holloway University of London, Egham, UK;
3Institute of Plant Biology, BRC, Szeged)

85.

Heat-induced responses in different clades of the coral endosymbiont algae, Symbiodiniaceae

Sabit Mohammad Aslam1,2, Milán Szabó1 and Imre Vass1

(1Institute of Plant Biology, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged)

86.

Algal-bacterial co-cultivation strategies to improve algal biomass and biohydrogen production

Prateek Shetty, Bernadett Pap, Attila Farkas, Bettina Hupp and Gergely Maróti

(Institute of Plant Biology, BRC, Szeged)

87.

The Retinoblastoma-related (RBR) controls thermomorphogenesis by regulating cell proliferation and cell enlargement in a temperature dependent manner

Rasik Shiekh1,2, Fruzsina Nagy1, Magdolna Gombos1, Aladár Pettkó-Szandtner3, Attila Fehér1,4 and Zoltán Magyar1.

(1Institute of Plant Biology, BRC, Szeged;
2Biological Doctoral School, University of Szeged, Szeged;
3Laboratory of Proteomics Research, BRC, Szeged;
4Department of Plant Biology, University of Szeged, Szeged)

88.

Light-adapted charge-separated state of Photosystem II. Structural and functional dynamics of the closed reaction center

Gábor Sipka1, Melinda Magyar1, Parveen Akhtar1,2, Stefano Santabarbara3, Pavel Müller4, Klaus Brettel4, Petar H. Lambrev1 and Győző Garab1,5

(1Institute of Plant Biology, BRC, Szeged;
2ELI-ALPS, ELI-HU Nonprofit Ltd., Szeged;
3Institute of Biophysics, NRC, Milano, Italy;
4Institute for Integrative Biology of the Cell, CEA, CNRS, Gif-sur-Yvette, France;
5Faculty of Science, University of Ostrava, Ostrava, Czech Republic)

89.

The chloroplastic phosphate transporter CrPHT4-7 supports phosphate homeostasis and photosynthesis in Chlamydomonas reinhardtii

Dávid Tóth1,2, Soujanya Kuntam1, Áron Ferenczi3, André Vidal-Meireles1, László Kovács1, Lianyong Wang4, Zsuzsa Sarkadi5, Ede Migh5, Juliane Neupert6, Ralph Bock6, Martin C. Jonikas4, Attila Molnar3 and Szilvia Z. Tóth1

(1Institute of Plant Biology, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Institute of Molecular Plant Sciences, University of Edinburgh, United Kingdom;
4Department of Molecular Biology, Princeton University, Princeton, United States;
5Institute of Biochemistry, BRC, Szeged;
6Max Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany)

90.

Comparison of different genome-editing technologies for herbicide tolerance in maize (Zea mays) cell cultures.

Szabolcs Török1,2, Zoltán Zombori1, Katalin Török1, Györgyi Ferenc1 and Dénes Dudits1

(1Institute of Plant Biology, BRC, Szeged;
2Deparetment of Plant Biology, University of Szeged, Szeged)