straub napok

A Szegedi Biológiai Kutatóközpont "Straub-Napok" rendezvénye - a több éves kényszerszünet után – 2023-ban újra a hagyományoknak megfelelően kerül megtartásra. A rendezők minden érdeklődőt szeretettel várnak.

A rendezvény kiemelt témája ezévben az evolúcióbiológia; az előadások témái lefedik az evolúciókutatás mind elméleti, mind alkalmazott aspektusait és bemutatják, hogy lehet az evolúciós megközelítéseket felhasználni a biológia régi és új nagy kérdéseinek megválaszolására, valamint akár gomba biotechnológiával és rákkutatással kapcsolatos innovatív projektekben is.

Az SZBK "Straub-Napok 2023" rendezvénye a Szegedi Biológiai Kutatóközpont és a Hungarian Centre of Excellence of Molecular Medicine társszervezésében kerül megrendezésre.

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elso nap 2023. május 25. csütörtök
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09:00 – 09:05
Nagy Ferenc
(Szegedi Biológiai Kutatóközpont, Szeged)
Megnyitó
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09:05 – 09:20
Nagy Ferenc
(Szegedi Biológiai Kutatóközpont, Szeged)
Főigazgatói beszámoló
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09:20 – 09:35
Ludányiné Tamás Anikó
(Szegedi Biológiai Kutatóközpont, Szeged)
Gazdasági beszámoló
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09:35 – 09:50
Hotchkiss Alapítvány, Qualitas Biologica Alapítvány és SZBK kiváló dolgozója díjazottak bemutatása és díjátadója
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09:50 – 10:00
Szünet
Chairman: Ferenc Nagy
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10:00 – 10:30
László Nagy
(Johns Hopkins University School of Medicine, St. Petersburg and University of Debrecen, Debrecen)
How macrophages harm and heal skeletal muscle: lessons from snake bites help understand and treat Duchenne Muscular Dystrophy
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10:30 – 11:00
László G. Nagy
(Institute of Biochemistry, BRC, Szeged)
Repeated evolutionary transitions in the fungal world
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11:00 – 11:30
Gergely János Szöllősi
(Institute of Physics and Astronomy, Eötvös Lorand University, Budapest)
Using protein language models to understand sequence evolution
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11:30 – 12:00
Gábor Boross
(Department of Biology, Stanford University, Stanford)
In vivo landscape of tumor suppressor interactions in lung adenocarcinoma
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12:00 – 13:00
Lunch break
Chairman: László Zimányi
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13:00 – 13:30
Gergő Porkoláb1,2, Mária Mészáros1, Anikó Szecskó1, Judit P Vigh1,2, Fruzsina R Walter1, Ricardo Figueiredo3, Fabien Gosselet4, Szilvia Veszelka1, Mária A Deli1
(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3GenXPro GmbH, Frankfurt am Main;
4Laboratoire de la Barriére Hémato-Encéphalique (LBHE), Université d’Artois, Lens)
Robust induction of blood-brain barrier properties by simultaneous targeting of signaling pathways
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13:30 – 14:00
Lejla Daruka1,2, Márton Czikkely1,2, Zoltán Farkas1,2, Petra Szili1,2, Szilvia Juhász1,2, Csaba Pál1,2
(1Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
2National Laboratory of Biotechnology, Szeged)
Antibiotics of the future are prone to bacterial resistance
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14:00 – 14:30
Zsófia Varga1, Eszter Váradi1,2, Gergely Nagy3, Edit Kotogány4, Petros Tzerpos3, Krisztián Bene3, Dóra Bojcsuk3, Anett Mázló5, Szilárd Poliska3, Attila Bácsi5,6, László Nagy3,7, Gábor Szebeni4, Zsolt Czimmerer1
(1Laboratory of Macrophage Polarization, Institute of Genetics, BRC, Szeged;
2Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged;
3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen;
4Laboratory of Functional Genomics, BRC, Szeged;
5Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen;
6ELKH-DE Allergology Research Group, Debrecen;
7Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children’s Hospital, St. Petersburg)
The unorthodox regulatory role of STAT6 and STAT1 transcription factors in macrophages
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14:30 – 15:00
Tibor Janda
(Agricultural Institute, Centre for Agricultural Research, Martonvásár)
Temperature acclimation processes in plants
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15:00 – 15:15
Coffee break
Chairman: Péter Horváth
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15:15 – 15:45
Prateek Shetty, Bernadett Pap, Attila Farkas, Gergely Maróti
(Institute of Plant Biology, BRC, Szeged)
Uncovering the molecular mechanisms underlying microalgae interactions with biotic and abiotic factors
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15:45 – 16:15
András Búzás1, Gergely T. Iványi1, Krisztina Nagy1, Ágnes Ábráhám1, Lóránd Kelemen1, Péter Galajda1, Pál Ormos1, Roberto Di Leonardo2,3, Gaszton Vizsnyiczai1,4
(1Institute of Biophysics, BRC, Szeged;
2Dipartimento di Fisica, Sapienza Università di Roma, Rome;
3NANOTEC-CNR, Soft and Living Matter Laboratory, Institute of Nanotechnology, Rome;
4Department of Biotechnology, University of Szeged, Szeged)
Flagellated microswimmers as active matter systems
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16:15 – 16:45
Xiao-Bin Liu, Zhihao Hou, Máté Virágh, Árpád Csernetics, Viktória Bense, Manish Pareek, Hongli Wu, Zsolt Merényi, Botond Hegedüs, László G. Nagy
(Institute of Biochemistry, BRC, Szeged)
Conserved transcription factors regulate the simple to complex multicellular transition in mushroom-forming fungi
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16:45 – 17:15
Judit Tóth
(Institute of Enzymology, Research Centre for Natural Sciences, Budapest)
DNA precursor metabolism and genomic integrity
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17:15 – 18:00
Poster session
elso nap 2023. május 26. péntek
Chairman: Miklós Erdélyi
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9:00 – 9:30
Erika Gábor1, Blanka Perenyei-Gerecs1,2, Bayan Kharrat1,2, Ede Migh3, Attila Beleon3, Péter Horváth3, Bence Széplaki4, Márton Enyedi4, Lajos Pintér4, Lajos Haracska4, Balázs Vedelek5, Viktor Honti1
(1Drosophila Blood Cell Differentiation Group, Institute of Genetics, BRC, Szeged;
2Faculty of Science and Informatics, University of Szeged, Szeged;
3Laboratory of Microscopic Image Analysis and Machine Learning, Institute of Biochemistry, BRC, Szeged;
4Laboratory of Mutagenesis and Carcinogenesis Research, Institute of Genetics, BRC, Szeged;
5Laboratory of Actin Cytoskeleton Regulation, Institute of Genetics, BRC, Szeged)
Post-transcriptional analysis of Drosophila blood cells
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9:30 – 10:00
Éva Kondorosi
(Institute of Plant Biology, BRC, Szeged)
Biological nitrogen fixation: a path to sustainable agriculture
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10:00 – 10:30
Attila-Gergely Végh1, Katalin Csonti1,2,3, Csilla Fazakas1, Kinga Molnár1, Imola Wilhelm1,4, István A. Krizbai1,4
(1Institute of Biophysics, BRC, Szeged;
2Doctoral School of Physics, University of Szeged, Szeged
3Semilab Semiconductor Physics Laboratory Co. Ltd., Budapest;
4Institute of Life Sciences, Vasile Goldiş Western University, Arad)
The force awakens: interaction of brain seeking metastatic tumor cells with the neurovascular unit
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10:30 – 11:00
Christoph W. Sensen
(Hungarian Centre of Excellence for Molecular Medicine, Szeged)
HCEMM in 2023: switching from construction to production mode
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11:00 – 11:15
Coffee Break
Chairman: Imre Vass
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11:15 – 11:45
Gábor Apjok1,2, András Asbóth1,2, Tóbiás Sári1,2, Lilla Barna2,3, Szilvia Juhász1, Ildikó Lantos1, Mária Deli3, Andrey Shkoporov4, Bálint Kintses1
(1Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Department of Biophysics, University of Szeged, Szeged;
4APC Microbiome Ireland & School of Microbiology, University College Cork, Co. Cork)
Genetic rewiring of phages for augmented therapeutic applications against antibiotic-resistant pathogens
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11:45 – 12:15
Hasan Mamar1,2, Eva Pinto1,3, Alexandra Mihut1,3, Anna Kopasz1,3, Mihály Mérey1,3, Roberta Fajka-Boja1, Gyula Timinszky1
(1Laboratory of DNA Damage and Nuclear Dynamics, Institute of Genetics, BRC, Szeged;
2Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged;
3Doctoral School of Multidisciplinary Medical Science, Faculty of Medicine, University of Szeged, Szeged)
The role of DNA polymerase epsilon accessory subunits POLE3 and POLE4 in PARP inhibitor sensitivity
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12:15 – 12:45
Magdolna Gombos1, Cécile Raynaud2, Eszter Molnár1, Dóri Bernula1, Fruzsina Nagy1,5, Xiaoning He2, Hidekazu Iwakawa3, Erika Őszi1, Jing An2, Csaba Papdi4, Clara Bergis2, Moussa Benhamed2, László Bögre4, Masaki Ito3, Zoltán Magyar1
(1Institute of Plant Biology, BRC, Szeged;
2Université Paris-Saclay, CNRS, INRAE, Université Evry, IPS2, Gif-sur-Yvette;
3School of Biological Science and Technology, College of Science and Engineering, Kanazawa University, Kanazawa;
4Royal Holloway, University of London, Department of Biological Sciences, Egham;
5Doctoral School in Biology, University of Szeged, Szeged;
6College of Bioscience and Biotechnology, Chubu University, Kasugai)
The canonical E2Fs together with RETINOBLASTOMA-RELATED are required to establish quiescence during plant development
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12:45 – 13:15
Róbert Horváth
(Research Institute for Technical Physics and Materials Science, Centre for Energy Research, Budapest)
Label-free single-cell biosensing and manipulation
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13:15 – 14:15
Lunch break
Chairman: Tamás Fehér
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14:15 – 14:45
Sándor Valkai, Dániel Petrovszki, Fruzsina R. Walter, Judit P. Vígh, Anna E. Kocsis, Mária A. Deli, András Dér
(Institute of Biophysics, BRC, Szeged)
Could the SARS-CoV-2 S1 subunit cross the blood-brain barrier? -- a lab-on-a-chip model study
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14:45 – 15:00
Arijit Sarkar1, Argha Mitra1, Szabolcs Dvorácskó1, Tamás Milán Nagy2,3, László Bence Farkas2,3, Márk Racskó4, Mária Harmati5, Krisztina Buzás5, Balázs István Tóth4, Zoltán Lipinszki6, Katalin E. Kövér2,3, Attila Borics1
(1Laboratory of Chemical Biology, Institute of Biochemistry, BRC, Szeged;
2Department of Inorganic and Analytical Chemistry, University of Debrecen, Debrecen;
3MTA-DE Molecular Recognition and Interaction Research Group, University of Debrecen, Debrecen;
4Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen;
5Lendület Laboratory of Microscopic Image Analysis and Machine Learning, Institute of Biochemistry, BRC, Szeged;
6Lendület Laboratory of Cell Cycle Regulation, Institute of Biochemistry, BRC, Szeged)
The role of correlated motions of conserved polar motifs and the binding modes of agonists in the activation mechanism of G protein-coupled receptors
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15:00 – 15:15
Walliyulahi Ajibola1,2, Roland Tengölics1,3, Csaba Tömböly4, Éva Klement3,5, Zsuzsanna Darula3,5, Tamás Fehér1,2
(1Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
2National Laboratory of Biotechnology, Szeged;
3Core Facilities, BRC, Szeged;
4Laboratory of Biological Chemistry, Institute of Biochemistry, BRC, Szeged;
5Single Cell Omics Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine, Szeged)
Isolation and engineering of soil bacteria producing novel antimicrobial peptides
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15:15 – 15:45
Áron Szabó1, Virág Vincze1,2, Aishwarya Sanjay Chhatre1,3, Sarolta Bognár1, Katalin Eszter Varga1, Poulami Banik1, András Jipa1, Adél Harmatos-Ürmösi1, Lukas J. Neukomm4, Gábor Juhász1,5
(1Lysosomal Degradation Research Group, Institute of Genetics, BRC, Szeged;
2Faculty of Science and Informatics, University of Szeged, Szeged;
3Doctoral School of Biology, Faculty of Science and Informatics, University of Szeged, Szeged;
4Department of Fundamental Neurosciences, University of Lausanne, Lausanne;
5Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest)
LC3-associated phagocytosis promotes glial degradation of axon debris after injury
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15:45 – 16:15
Anita Hajdu1, Dóra V. Nyári1,2, Dániel Silhavy1, Ferenc Nagy1, László Kozma-Bognár1,3
(1Institute of Plant Biology, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Department of Genetics, Faculty of Science and Informatics, University of Szeged, Szeged)
Identification of a conserved serine residue critical for the catalytic activity of UBIQUITIN-SPECIFIC PROTEASE 12, a modulator of the plant circadian clock
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16:15 – 17:00
Poster session
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19:00 –
Conference dinner
Posters
INSTITUTE OF BIOCHEMISTRY
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1.
The role of correlated motions of conserved polar motifs and the binding modes of agonists in the activation mechanism of G protein-coupled receptors
Arijit Sarkar1, Argha Mitra1, Szabolcs Dvorácskó1, Tamás Milán Nagy2,3, László Bence Farkas2,3, Márk Racskó4, Mária Harmati5, Krisztina Buzás5, Balázs István Tóth4, Zoltán Lipinszki6, Katalin E. Kövér2,3, Attila Borics1
(1Laboratory of Chemical Biology, Institute of Biochemistry, BRC, Szeged;
2Department of Inorganic and Analytical Chemistry, University of Debrecen, Debrecen;
3MTA-DE Molecular Recognition and Interaction Research Group, University of Debrecen, Debrecen;
4Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen;
5Lendület Laboratory of Microscopic Image Analysis and Machine Learning, Institute of Biochemistry, BRC, Szeged;
6Lendület Laboratory of Cell Cycle Regulation, Institute of Biochemistry, BRC, Szeged)
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Unannotated genes regulate fruiting body morphogenesis of the Basidiomycota model organism Coprinopsis cinerea
Csenge Földi1, Zsolt Merényi1, László Galgóczi2, László G. Nagy1
(1Institute of Biochemistry, BRC, Szeged;
2Department of Biotechnology, University of Szeged, Szeged)
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DS4H Image Alignment (DS4H-IA), an open-source ImageJ/Fiji plugin for aligning multimodality 2D microscopy images
Filippo Piccinini1,2, Vincenzi Fabio3, Iorio Matteo3, Marcella Tazzari1, Maria Maddalena Tumedei1, Jae-Chul Pyun4, Enrico Giampieri2, Giovanni Martinelli1, Gastone Castellani2 , Antonella Carbonaro5
(1IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola (FC);
2Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna;
3Student, Computer Science and Engineering, University of Bologna, Bologna;
4Department of Materials Science & Engineering, Yonsei University, Seoul;
5Department of Computer Science and Engineering (DISI), University of Bologna, Bologna)
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Plk4 is a novel substrate of Protein phosphatase 5
Edit Ábrahám1, Zsuzsánna Réthi-Nagy1, Péter Vilmos2, Rita Sinka3, Zoltán Lipinszki1
(1Institute of Biochemistry, BRC, Szeged;
2Institute of Genetics, BRC, Szeged;
3Department of Genetics, University of Szeged, Szeged)
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5.
Protein phosphatase 4 is required for Centrobin function in DNA damage repair
Zsuzsánna Réthi-Nagy1,2, Edit Ábrahám1, Rita Sinka3, Szilvia Juhász1, Zoltán Lipinszki1
(1Institute of Biochemistry, BRC, Szeged;
2Doctoral School of Biology, University of Szeged, Szeged;
3Department of Genetics, University of Szeged, Szeged)
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6.
Investigation of gene regulatory networks underlying pattern formation in Coprinopsis cinerea
Hongli Wu, Xiao-Bin Liu, Torda Varga, Máté Virágh, Zhihao Hou, Zsolt Merényi, Botond Hegedüs, László G. Nagy
(Synthetic and Systems Biology Unit, BRC, Szeged)
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7.
What does the evolution of the mammalian metabolome reveal about human diseases?
Lilla Széles1, István Magyary1, Orsolya Liska1,2,3, Balázs Szappanos1,2,4, Balázs Papp1,2
(1Synthetic and Systems Biology Unit, Institute of Biochemistry, BRC, Szeged;
2HCEMM-BRC Metabolic Systems Biology Lab, Szeged;
3Doctoral School of Biology, University of Szeged, Szeged;
4Department of Biotechnology, University of Szeged, Szeged)
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Exploring tail fiber diversity and compatibility among Caudovirales using comparative genomics
András Asbóth1,2, Tamás Stirling1, Bálint Márk Vásárhelyi1, Gábor Apjok1, Eszter Ari1,2, Victor Klein De Sousa3, Bálint Kintses1
(1Institute of Biochemistry, BRC, Szeged;
2Department of Genetics, Eötvös Loránd University, Budapest;
3Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen)